In vivo evidence for the selective subcortical degeneration in Huntington's disease

Introduction Although Huntington's disease (HD) is largely considered to be a subcortical disease, there is no clear consensus on whether all the deep grey matter loss is a direct downstream consequence of the massive death of medium-size spiny neurons in the striatum.

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2009-07, Vol.47, p.S93-S93
Hauptverfasser:	DOUAUD, G., BEHRENS, T., POUPON, C., COINTEPAS, Y., JBABDI, S., GAURA, V., GOLESTANI, N., KRYSTKOWIAK, P., VERNY, C., DAMIER, P., BACHOUD-LEVI, A.-C, HANTRAYE, P., REMY, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Huntingtons disease
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Introduction Although Huntington's disease (HD) is largely considered to be a subcortical disease, there is no clear consensus on whether all the deep grey matter loss is a direct downstream consequence of the massive death of medium-size spiny neurons in the striatum.
ISSN:	1053-8119 1095-9572
DOI:	10.1016/S1053-8119(09)70744-X