995 Impact of Ventilator-Associated Pneumonia on Treatment and Length of Stay in Critically Pediatric Patients with Lower Respiratory System Infection
Background and Aims Ventilator-associated pneumonia (VAP) may complicate the hospital course in critically ill children with pneumonia or bronchiolitis admitted to PICU. We compared the outcomes and treatment in PICU patients with pneumonia or bronchiolitis who developed VAP and those without VAP. M...
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| Veröffentlicht in: | Archives of disease in childhood 2012-10, Vol.97 (Suppl 2), p.A284-A285 |
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| creator | Stabouli, S Violaki, A Volakli, E Vogiatzi, L Skoumis, K Sdougka, M |
| description | Background and Aims Ventilator-associated pneumonia (VAP) may complicate the hospital course in critically ill children with pneumonia or bronchiolitis admitted to PICU. We compared the outcomes and treatment in PICU patients with pneumonia or bronchiolitis who developed VAP and those without VAP. Methods The medical records of PICU patients with pneumonia or bronchiolitis from January 2011 to December 2011 in a tertiary care hospital were reviewed. Demographic and clinical data including antibiotic therapy were recorded.VAP was diagnosed according to CDC criteria. Results 28 patients were recruited, 12(42%) with VAP and 14(58%) without VAP, mean age 3.7±1.1 and 3.6±4.7, respectively. PRISM III score at admission, comorbidity (chronic lung disease, cardiopathy, mental retardation, malnutrition or obesity, immunosuppression),antacid medication and systemic steroid use were similar in both groups. The most common VAP pathogens were gram(-) bacteria (Acinetobacter baumannii and Pseudomonas aeruginosa). Antibiotics use in the 2 groups are shown in figure 1. Abstract 995 Figure 1 Patients with VAP received longer treatment with aminoglucisides compared with patients without VAP (18.42±13.02 vs. 6.25±5.19 days, P |
| doi_str_mv | 10.1136/archdischild-2012-302724.0995 |
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We compared the outcomes and treatment in PICU patients with pneumonia or bronchiolitis who developed VAP and those without VAP. Methods The medical records of PICU patients with pneumonia or bronchiolitis from January 2011 to December 2011 in a tertiary care hospital were reviewed. Demographic and clinical data including antibiotic therapy were recorded.VAP was diagnosed according to CDC criteria. Results 28 patients were recruited, 12(42%) with VAP and 14(58%) without VAP, mean age 3.7±1.1 and 3.6±4.7, respectively. PRISM III score at admission, comorbidity (chronic lung disease, cardiopathy, mental retardation, malnutrition or obesity, immunosuppression),antacid medication and systemic steroid use were similar in both groups. The most common VAP pathogens were gram(-) bacteria (Acinetobacter baumannii and Pseudomonas aeruginosa). Antibiotics use in the 2 groups are shown in figure 1. Abstract 995 Figure 1 Patients with VAP received longer treatment with aminoglucisides compared with patients without VAP (18.42±13.02 vs. 6.25±5.19 days, P<0.01). Moreover, only children with VAP were treated with quinolones. Patients with VAP had also significantly increased length of PICU stay(LOS) and mechanical ventilation. (figure 2). Abstract 995 Figure 2 Conclusions VAP occurs in a significant proportion of PICU patients with lower respiratory infection resulting in increased LOS and antibiotic use.</description><identifier>ISSN: 0003-9888</identifier><identifier>EISSN: 1468-2044</identifier><identifier>DOI: 10.1136/archdischild-2012-302724.0995</identifier><identifier>CODEN: ADCHAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</publisher><subject>Anatomy ; Antibiotics ; Malnutrition ; Obesity ; Patients ; Respiratory system ; Ventilation</subject><ispartof>Archives of disease in childhood, 2012-10, Vol.97 (Suppl 2), p.A284-A285</ispartof><rights>2012, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>Copyright: 2012 (c) 2012, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://adc.bmj.com/content/97/Suppl_2/A284.4.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://adc.bmj.com/content/97/Suppl_2/A284.4.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,3183,23550,27901,27902,77343,77374</link.rule.ids></links><search><creatorcontrib>Stabouli, S</creatorcontrib><creatorcontrib>Violaki, A</creatorcontrib><creatorcontrib>Volakli, E</creatorcontrib><creatorcontrib>Vogiatzi, L</creatorcontrib><creatorcontrib>Skoumis, K</creatorcontrib><creatorcontrib>Sdougka, M</creatorcontrib><title>995 Impact of Ventilator-Associated Pneumonia on Treatment and Length of Stay in Critically Pediatric Patients with Lower Respiratory System Infection</title><title>Archives of disease in childhood</title><addtitle>Arch Dis Child</addtitle><description>Background and Aims Ventilator-associated pneumonia (VAP) may complicate the hospital course in critically ill children with pneumonia or bronchiolitis admitted to PICU. We compared the outcomes and treatment in PICU patients with pneumonia or bronchiolitis who developed VAP and those without VAP. Methods The medical records of PICU patients with pneumonia or bronchiolitis from January 2011 to December 2011 in a tertiary care hospital were reviewed. Demographic and clinical data including antibiotic therapy were recorded.VAP was diagnosed according to CDC criteria. Results 28 patients were recruited, 12(42%) with VAP and 14(58%) without VAP, mean age 3.7±1.1 and 3.6±4.7, respectively. PRISM III score at admission, comorbidity (chronic lung disease, cardiopathy, mental retardation, malnutrition or obesity, immunosuppression),antacid medication and systemic steroid use were similar in both groups. The most common VAP pathogens were gram(-) bacteria (Acinetobacter baumannii and Pseudomonas aeruginosa). Antibiotics use in the 2 groups are shown in figure 1. Abstract 995 Figure 1 Patients with VAP received longer treatment with aminoglucisides compared with patients without VAP (18.42±13.02 vs. 6.25±5.19 days, P<0.01). Moreover, only children with VAP were treated with quinolones. Patients with VAP had also significantly increased length of PICU stay(LOS) and mechanical ventilation. (figure 2). Abstract 995 Figure 2 Conclusions VAP occurs in a significant proportion of PICU patients with lower respiratory infection resulting in increased LOS and antibiotic use.</description><subject>Anatomy</subject><subject>Antibiotics</subject><subject>Malnutrition</subject><subject>Obesity</subject><subject>Patients</subject><subject>Respiratory system</subject><subject>Ventilation</subject><issn>0003-9888</issn><issn>1468-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNqVkc1O3DAURq2qSJ0C72AJdRnqnyR2Fl2gUQsjBRjBwIKN5TgO42liT22PaF6E58VRqootK0tX59xPvh8A3zA6x5iW36VX29YEtTV9mxGESUYRYSQ_R1VVfAILnJc8zfP8M1gghGhWcc6_gK8h7FCiOacL8JpQuBr2UkXoOviobTS9jM5nFyE4ZWTULVxbfRicNRI6CzdeyzgkDkrbwlrb57id1PsoR2gsXHoTjZJ9P8K1btMCbxRcy2iSEuCLSXTtXrSHdzrsjZ-yRng_hqgHuLKdVtE4ewKOOtkHffrvPQYPv35ulldZfXu5Wl7UWUNIXmSs1UirFnHKWNWQJid5yZBirOGoVazsJOqqostpRwumSYMl1YopiuREqYoeg7N57967Pwcdoti5g7cpUmCeLlSmc_JE_Zgp5V0IXndi780g_SgwElMV4n0VYqpCzFWIqYrkZ7Nv0i___pel_y1KRlkhbh6X4qrGm-v107WY8vjMN8Pug1Fv3hykaQ</recordid><startdate>201210</startdate><enddate>201210</enddate><creator>Stabouli, S</creator><creator>Violaki, A</creator><creator>Volakli, E</creator><creator>Vogiatzi, L</creator><creator>Skoumis, K</creator><creator>Sdougka, M</creator><general>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88B</scope><scope>88E</scope><scope>88I</scope><scope>8A4</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0P</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope></search><sort><creationdate>201210</creationdate><title>995 Impact of Ventilator-Associated Pneumonia on Treatment and Length of Stay in Critically Pediatric Patients with Lower Respiratory System Infection</title><author>Stabouli, S ; Violaki, A ; Volakli, E ; Vogiatzi, L ; Skoumis, K ; Sdougka, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b2245-7de0ecd083779b2b424670c77b80dc76fa0f95f43f357e2b1a3ec7c30a70c7c93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Anatomy</topic><topic>Antibiotics</topic><topic>Malnutrition</topic><topic>Obesity</topic><topic>Patients</topic><topic>Respiratory system</topic><topic>Ventilation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stabouli, S</creatorcontrib><creatorcontrib>Violaki, A</creatorcontrib><creatorcontrib>Volakli, E</creatorcontrib><creatorcontrib>Vogiatzi, L</creatorcontrib><creatorcontrib>Skoumis, K</creatorcontrib><creatorcontrib>Sdougka, M</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Education Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Education Periodicals</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Education Collection</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Education Database</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Education</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><jtitle>Archives of disease in childhood</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stabouli, S</au><au>Violaki, A</au><au>Volakli, E</au><au>Vogiatzi, L</au><au>Skoumis, K</au><au>Sdougka, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>995 Impact of Ventilator-Associated Pneumonia on Treatment and Length of Stay in Critically Pediatric Patients with Lower Respiratory System Infection</atitle><jtitle>Archives of disease in childhood</jtitle><addtitle>Arch Dis Child</addtitle><date>2012-10</date><risdate>2012</risdate><volume>97</volume><issue>Suppl 2</issue><spage>A284</spage><epage>A285</epage><pages>A284-A285</pages><issn>0003-9888</issn><eissn>1468-2044</eissn><coden>ADCHAK</coden><abstract>Background and Aims Ventilator-associated pneumonia (VAP) may complicate the hospital course in critically ill children with pneumonia or bronchiolitis admitted to PICU. We compared the outcomes and treatment in PICU patients with pneumonia or bronchiolitis who developed VAP and those without VAP. Methods The medical records of PICU patients with pneumonia or bronchiolitis from January 2011 to December 2011 in a tertiary care hospital were reviewed. Demographic and clinical data including antibiotic therapy were recorded.VAP was diagnosed according to CDC criteria. Results 28 patients were recruited, 12(42%) with VAP and 14(58%) without VAP, mean age 3.7±1.1 and 3.6±4.7, respectively. PRISM III score at admission, comorbidity (chronic lung disease, cardiopathy, mental retardation, malnutrition or obesity, immunosuppression),antacid medication and systemic steroid use were similar in both groups. The most common VAP pathogens were gram(-) bacteria (Acinetobacter baumannii and Pseudomonas aeruginosa). Antibiotics use in the 2 groups are shown in figure 1. Abstract 995 Figure 1 Patients with VAP received longer treatment with aminoglucisides compared with patients without VAP (18.42±13.02 vs. 6.25±5.19 days, P<0.01). Moreover, only children with VAP were treated with quinolones. Patients with VAP had also significantly increased length of PICU stay(LOS) and mechanical ventilation. (figure 2). Abstract 995 Figure 2 Conclusions VAP occurs in a significant proportion of PICU patients with lower respiratory infection resulting in increased LOS and antibiotic use.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</pub><doi>10.1136/archdischild-2012-302724.0995</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Anatomy Antibiotics Malnutrition Obesity Patients Respiratory system Ventilation |
| title | 995 Impact of Ventilator-Associated Pneumonia on Treatment and Length of Stay in Critically Pediatric Patients with Lower Respiratory System Infection |
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