Intestinal infection at onset of mycophenolic acid-associated chronic diarrhea in kidney transplant recipients

Background Chronic diarrhea after kidney transplantation is often attributed to mycophenolic acid (MPA) toxicity. We hypothesize that intestinal infections contribute to the pathogenesis of chronic MPA‐associated diarrhea. Methods In this retrospective study, all patients (n = 726) receiving a kidne...

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Veröffentlicht in:	Transplant infectious disease 2016-10, Vol.18 (5), p.721-729
Hauptverfasser:	von Moos, S., Cippà, P.E., Wüthrich, R.P., Mueller, T.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Area Under Curve Chronic Disease chronic post-transplant diarrhea Colitis - epidemiology Colitis - etiology Colitis - physiopathology Colon - microbiology Colon - pathology Diarrhea Diarrhea - epidemiology Diarrhea - etiology Diarrhea - physiopathology Feces - microbiology Female Follow-Up Studies Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - adverse effects Incidence infectious trigger intestinal infection Kidney Transplantation - adverse effects Male Middle Aged Mycophenolic Acid - administration & dosage Mycophenolic Acid - adverse effects Mycophenolic Acid - therapeutic use mycophenolic acid-related diarrhea Persian Gulf War Retrospective Studies Switzerland - epidemiology Transplant Recipients Transplantation, Homologous - adverse effects Transplants & implants Weight Loss
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