NMNAT3 is involved in the protective effect of SIRT3 in Ang II-induced cardiac hypertrophy

Pathological cardiac hypertrophy is a maladaptive response in a variety of organic heart disease (OHD), which is characterized by mitochondrial dysfunction that results from disturbed energy metabolism. SIRT3, a mitochondria-localized sirtuin, regulates global mitochondrial lysine acetylation and pr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental cell research 2016-10, Vol.347 (2), p.261-273
Hauptverfasser:	Yue, Zhongbao, Ma, Yunzi, You, Jia, Li, Zhuoming, Ding, Yanqing, He, Ping, Lu, Xia, Jiang, Jianmin, Chen, Shaorui, Liu, Peiqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Angiotensin II Animals Animals, Newborn Cardiac hypertrophy Cardiomegaly - metabolism Cardiomegaly - pathology Cardiotonic Agents - metabolism Cardiovascular disease Down-Regulation Fluorescent Antibody Technique Heart Intracellular Space - metabolism Male Metabolism Mice, Knockout Mitochondria Mitochondria - metabolism Models, Biological Myocytes, Cardiac - metabolism Myocytes, Cardiac - pathology Nicotinamide Phosphoribosyltransferase - metabolism Nicotinamide-Nucleotide Adenylyltransferase - metabolism NMNAT3 Pathology Protein Binding Rats RNA, Messenger - genetics RNA, Messenger - metabolism SIRT3 Sirtuin 3 - genetics Sirtuin 3 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!