When [beta]-cells fail: lessons from dedifferentiation

Diabetes is caused by a combination of impaired responsiveness to insulin and reduced production of insulin by the pancreas. Until recently, the decline of insulin production had been ascribed to [beta]-cell death. But recent research has shown that [beta]-cells do not die in diabetes, but undergo a...

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Veröffentlicht in:Diabetes, obesity & metabolism obesity & metabolism, 2016-09, Vol.18 (S1), p.117
Hauptverfasser: Accili, D, Talchai, S C, Kim-Muller, J Y, Cinti, F, Ishida, E, Ordelheide, A M, Kuo, T, Fan, J, Son, J
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Sprache:eng
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