Interleukin-1[beta] Mediates [beta]-Catenin-Driven Downregulation of Claudin-3 and Barrier Dysfunction in Caco2 Cells

Background IL-1[beta] is a cytokine involved in mediating epithelial barrier dysfunction in the gut. It is known that IL-1[beta] mediates activation of non-muscle myosin light chain kinase in epithelial cells, but the precise mechanism by which epithelial barrier dysfunction is induced by IL-1[beta]...

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Veröffentlicht in:Digestive diseases and sciences 2016-08, Vol.61 (8), p.2252
Hauptverfasser: Haines, R. J, Beard, R. S, Chen, L, Eitnier, R. A, Wu, M. H
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Sprache:eng
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