Targeting [beta]1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice

Interactions between stem cells and their microenvironment, or niche, are essential for stem cell maintenance and function. Our knowledge of the niche for the skeletal muscle stem cell, i.e., the satellite cell (SC), is incomplete. Here we show that 1-integrin is an essential niche molecule that mai...

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Veröffentlicht in:	Nature medicine 2016-08, Vol.22 (8), p.889
Hauptverfasser:	Rozo, Michelle, Li, Liangji, Fan, Chen-ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Dystrophy Muscles Musculoskeletal system Rodents Stem cells
Online-Zugang:	Volltext
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