38 STATINS AS TISSUE-SPECIFIC INDUCERS OF IN VIVO HEME OXYGENASE EXPRESSION

Heme oxygenase (HO) is the rate-limiting enzyme in degrading heme to form bilirubin, and thus serves as an ideal therapeutic target for preventing neonatal jaundice. Understanding the regulatory pathways of HO is crucial for developing strategies for this disorder. Statins, inhibitors of 3-hydroxyl-...

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Veröffentlicht in:Journal of investigative medicine 2006-01, Vol.54 (1), p.S86-S86
Hauptverfasser: Hsu, M., Muchova, L., Morioka, I., Wong, R. J., Schröder, H., Stevenson, D. K.
Format: Artikel
Sprache:eng
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