TAp73 loss favors Smad-independent TGF-[beta] signaling that drives EMT in pancreatic ductal adenocarcinoma

Advances made in pancreatic cancer therapy have been far from sufficient and have allowed only a slight improvement in global survival of patients with pancreatic ductal adenocarcinoma (PDA). Recent progresses in chemotherapy have offered some hope for an otherwise gloomy outlook, however, only a li...

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Veröffentlicht in:	Cell death and differentiation 2016-08, Vol.23 (8), p.1358
Hauptverfasser:	Thakur, A K, Nigri, J, Lac, S, Leca, J, Bressy, C, Berthezene, P, Bartholin, L, Chan, P, Calvo, E, Iovanna, J L, Vasseur, S, Guillaumond, F, Tomasini, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell cycle Cell death Chemotherapy Cyclin-dependent kinases Extracellular matrix Fibroblasts Growth factors Kinases Medical prognosis Mutation Pancreatic cancer Proteins Roles Tumors
Online-Zugang:	Volltext
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