Synthesis, Spectral characterization and antimicrobial activity of 2-(substituted)-2,2-[1,3- dihydro-(3,4-1,2,5-oxadiazolediyl) diaza][5 , 5 -dimethyl-1 , 3 -propanediyl) dioxy] phosphoranes

Synthesis, Spectral characterization and antimicrobial activity of 2-(substituted)-2,2-[1,3- dihydro-(3,4-1,2,5-oxadiazolediyl) diaza][5 , 5 -dimethyl-1 , 3 -propanediyl) dioxy] phosphoranes

The cyclic oxadiazolediyl dioxachlorophosphine precursor on subsequent reaction with various alcohols underwent halide displacement to give 2-substituted diaza phospholes. These phospholes on oxidative addition with di hydroxy alcohols form corresponding phosphoranes The antimicrobial activities of...

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Veröffentlicht in:Organic communications 2010-01, Vol.3 (1), p.15
Hauptverfasser: Babu, Y Hari, A Uma Ravi Sankar, B Siva Kumar, Reddy, C Suresh
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description The cyclic oxadiazolediyl dioxachlorophosphine precursor on subsequent reaction with various alcohols underwent halide displacement to give 2-substituted diaza phospholes. These phospholes on oxidative addition with di hydroxy alcohols form corresponding phosphoranes The antimicrobial activities of these compounds were evaluated and they exhibited significant antimicrobial activity.
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title Synthesis, Spectral characterization and antimicrobial activity of 2-(substituted)-2,2-[1,3- dihydro-(3,4-1,2,5-oxadiazolediyl) diaza][5 , 5 -dimethyl-1 , 3 -propanediyl) dioxy] phosphoranes
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