Coptidis rhizoma extract protects against cytokine-induced death of pancreatic [beta]-cells through suppression of NF-[kappa] B activation

We demonstrated previously that Coptidis rhizoma extract (CRE) prevented S-nitroso-N-acetylpenicillamine-induced apoptotic cell death via the inhibition of mitochondrial membrane potential disruption and cytochrome c release in RINm5F (RIN) rat insulinoma cells. In this study, the preventive effects...

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Veröffentlicht in:Experimental & molecular medicine 2007-04, Vol.39 (2), p.149
Hauptverfasser: Kim, Eun-kyung, Kwon, Kang-beom, Han, Mi-jeong, Song, Mi-young, Lee, Ji-hyun, Lv, Na, Ka, Sun-o, Yeom, Seung-ryong, Kwon, Young-dal, Ryu, Do-gon, Kim, Kang-san, Park, Jin-woo, Park, Raekil, Park, Byung-hyun
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Sprache:eng
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