Squamous-Cell Carcinoma of the Tongue
A 73-year-old woman presented with a persistent ulcer and white patch on the right margin of the tongue. Intraoral examination revealed a superficial ulcer with a homogeneous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border. A 73-year-old woman presen...
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Veröffentlicht in: | The New England journal of medicine 2016-06, Vol.374 (25), p.e32 |
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description | A 73-year-old woman presented with a persistent ulcer and white patch on the right margin of the tongue. Intraoral examination revealed a superficial ulcer with a homogeneous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border.
A 73-year-old woman presented with a 1-year history of a persistent ulcer and white patch on the right margin of the tongue and soreness while eating. She did not smoke or drink alcohol. Extraoral examination revealed no cervical lymphadenopathy. Intraoral examination revealed a well-circumscribed superficial ulcer, measuring 7 mm by 3 mm in the greatest dimensions, with a homogeneous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border (Panel A). Incisional biopsy of the indurated upper border revealed invasive squamous-cell carcinoma (Panel B; hematoxylin and eosin). Incisional biopsy of the speckled area . . . |
doi_str_mv | 10.1056/NEJMicm1513456 |
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A 73-year-old woman presented with a 1-year history of a persistent ulcer and white patch on the right margin of the tongue and soreness while eating. She did not smoke or drink alcohol. Extraoral examination revealed no cervical lymphadenopathy. Intraoral examination revealed a well-circumscribed superficial ulcer, measuring 7 mm by 3 mm in the greatest dimensions, with a homogeneous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border (Panel A). Incisional biopsy of the indurated upper border revealed invasive squamous-cell carcinoma (Panel B; hematoxylin and eosin). Incisional biopsy of the speckled area . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMicm1513456</identifier><language>eng</language><publisher>Boston: Massachusetts Medical Society</publisher><subject>Biopsy ; Case reports ; Health risk assessment ; Oral cancer ; Squamous cell carcinoma ; Tongue ; Ulcers</subject><ispartof>The New England journal of medicine, 2016-06, Vol.374 (25), p.e32</ispartof><rights>Copyright © 2016 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-a2495158197e7aadc3388c5142ac4bce6754a4ca231fa2e1fe2f241b252125d23</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMicm1513456$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1799265647?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64385,64389,72341</link.rule.ids></links><search><creatorcontrib>Albuquerque, Rui P.P</creatorcontrib><creatorcontrib>Richards, Andrea</creatorcontrib><title>Squamous-Cell Carcinoma of the Tongue</title><title>The New England journal of medicine</title><description>A 73-year-old woman presented with a persistent ulcer and white patch on the right margin of the tongue. Intraoral examination revealed a superficial ulcer with a homogeneous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border.
A 73-year-old woman presented with a 1-year history of a persistent ulcer and white patch on the right margin of the tongue and soreness while eating. She did not smoke or drink alcohol. Extraoral examination revealed no cervical lymphadenopathy. Intraoral examination revealed a well-circumscribed superficial ulcer, measuring 7 mm by 3 mm in the greatest dimensions, with a homogeneous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border (Panel A). Incisional biopsy of the indurated upper border revealed invasive squamous-cell carcinoma (Panel B; hematoxylin and eosin). Incisional biopsy of the speckled area . . .</description><subject>Biopsy</subject><subject>Case reports</subject><subject>Health risk assessment</subject><subject>Oral cancer</subject><subject>Squamous cell carcinoma</subject><subject>Tongue</subject><subject>Ulcers</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kD1PwzAYhC0EEqGwMkdCsLn4tV_nY0RRy4cKDJTZcl0HEsVxazcD_56gsDBwyy3P3UlHyCWwOTCZ3b4snp4b40CCQJkdkQSkEBSRZcckYYwXFPNSnJKzGFs2CrBMyPXbftDOD5FWtuvSSgfT9N7p1Nfp4dOma99_DPacnNS6i_bi12fkfblYVw909Xr_WN2tqEFWHKjmWEqQBZS5zbXeGiGKwkhArg1ujM1yiRqN5gJqzS3UltccYcMlBy63XMzI1dS7C34_2HhQrR9CP04qyMuSZzLDfKTmE2WCjzHYWu1C43T4UsDUzxXq7xVj4GYKOBdVb1v3H_gNqudbEw</recordid><startdate>20160623</startdate><enddate>20160623</enddate><creator>Albuquerque, Rui P.P</creator><creator>Richards, Andrea</creator><general>Massachusetts Medical Society</general><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>20160623</creationdate><title>Squamous-Cell Carcinoma of the Tongue</title><author>Albuquerque, Rui P.P ; Richards, Andrea</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-a2495158197e7aadc3388c5142ac4bce6754a4ca231fa2e1fe2f241b252125d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Biopsy</topic><topic>Case reports</topic><topic>Health risk assessment</topic><topic>Oral cancer</topic><topic>Squamous cell carcinoma</topic><topic>Tongue</topic><topic>Ulcers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Albuquerque, Rui P.P</creatorcontrib><creatorcontrib>Richards, Andrea</creatorcontrib><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database (ProQuest)</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database (Proquest)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Family Health Database (Proquest)</collection><collection>Health Management Database (Proquest)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database (ProQuest)</collection><collection>ProQuest Research Library</collection><collection>ProQuest Science Journals</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Albuquerque, Rui P.P</au><au>Richards, Andrea</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Squamous-Cell Carcinoma of the Tongue</atitle><jtitle>The New England journal of medicine</jtitle><date>2016-06-23</date><risdate>2016</risdate><volume>374</volume><issue>25</issue><spage>e32</spage><pages>e32-</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>A 73-year-old woman presented with a persistent ulcer and white patch on the right margin of the tongue. Intraoral examination revealed a superficial ulcer with a homogeneous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border.
A 73-year-old woman presented with a 1-year history of a persistent ulcer and white patch on the right margin of the tongue and soreness while eating. She did not smoke or drink alcohol. Extraoral examination revealed no cervical lymphadenopathy. Intraoral examination revealed a well-circumscribed superficial ulcer, measuring 7 mm by 3 mm in the greatest dimensions, with a homogeneous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border (Panel A). Incisional biopsy of the indurated upper border revealed invasive squamous-cell carcinoma (Panel B; hematoxylin and eosin). Incisional biopsy of the speckled area . . .</abstract><cop>Boston</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJMicm1513456</doi><oa>free_for_read</oa></addata></record> |
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subjects | Biopsy Case reports Health risk assessment Oral cancer Squamous cell carcinoma Tongue Ulcers |
title | Squamous-Cell Carcinoma of the Tongue |
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