Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGF[beta] Type 1 Receptor Modulation by Antisense Oligonucleotides

Dupuytren's disease (DD) is a benign fibroproliferative disease of the hand. It is characterized by the excessive production of extracellular matrix (ECM) proteins, which form a strong fibrous tissue between the handpalm and fingers, permanently disrupting the fine movement ability. The major c...

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Veröffentlicht in:Molecular therapy. Nucleic acids 2014-01, Vol.3, p.e142
Hauptverfasser: Karkampouna, Sofia, Kruithof, Boudewijn Pt, Kloen, Peter, Obdeijn, Miryam C, Van Der Laan, Annelies Ma, Tanke, Hans J, Kemaladewi, Dwi U, Hoogaars, Willem Mh, 't Hoen, Peter Ac, Aartsma-rus, Annemieke, Clark, Ian M, Ten Dijke, Peter, Goumans, Marie-josé, Kruithof-de Julio, Marianna
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Sprache:eng
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