685. Epithelium-Specific Gene Therapy Vector Protects Cftr Knockout Mice from Acute Lung Infection

Development of safe and effective vectors remains a major challenge for lung gene therapy. We developed a helper-dependent adenoviral vector for cystic fibrosis (CF) lung gene therapy, using epithelium-specific control elements to drive expression of the CF transmembrane conductance regulator (Cftr)...

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Veröffentlicht in:	Molecular therapy 2004-05, Vol.9 (S1), p.S260-S260
Hauptverfasser:	Koehler, David R, Sajjan, Umadevi, Colin, Mckerlie, Coates, Allan, Tanswell, Keith, Janet, stner F, Hu, Jim
Format:	Artikel
Sprache:	eng
Schlagworte:	Cystic fibrosis Gene therapy Histopathology Lung cancer Lung diseases Medical research Tumorigenesis Vectors (Biology)
Online-Zugang:	Volltext
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