478. Preinjection of free DiC14-amidine liposome and dexamethasone synergistically enhance the intravenous transfection efficiency of cationic lipid/DNA lipoplex

Cationic lipids represent a safe alternative to viral vectors for gene therapy applications but their use is still limited by a low in vivo gene transfer efficiency. We report here that cationic lipid-mediated intravenous transfection efficiency can be improved by a single preinjection of free diC14...

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Veröffentlicht in:	Molecular therapy 2004-05, Vol.9 (S1), p.S181
Hauptverfasser:	Lonez, Caroline, Ruysschaert, Jean-marie, Elouahabi, Abdelatif
Format:	Artikel
Sprache:	eng
Schlagworte:	Artificial chromosomes Efficiency Flow cytometry Gene therapy Lipids Stem cells
Online-Zugang:	Volltext
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