A modular set of helper-dependent herpes simplex virus expression vectors

Herpes simplex virus (HSV) has many favorable properties in terms of its potential to serve as a delivery and expression platform for gene-based therapies, including the ability to establish persistent infections, a broad tissue tropism, episomal maintenance of transduced genes, and a large genome t...

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Veröffentlicht in:	Molecular therapy 2000-05, Vol.1 (5 Pt 1), p.479-485
Hauptverfasser:	Strathdee, C A, McLeod, M R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics beta-Galactosidase - biosynthesis Cercopithecus aethiops Cloning DNA Replication DNA, Viral - analysis DNA-Binding Proteins Drug resistance Gene Expression Gene therapy Genetic Vectors Genomes Green Fluorescent Proteins Helper Viruses - genetics Helper Viruses - metabolism Herpes viruses Humans Luminescent Proteins - biosynthesis Molecular Structure Nuclear Proteins - biosynthesis Simplexvirus - genetics Simplexvirus - metabolism Toxicity Transduction, Genetic Transfection - methods Vectors (Biology) Vero Cells Virus Assembly
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