807. NADPH-Dependent Endosomal ROS Is Critical for rAAV Capsid Processing during Infection

Reactive oxygen species (ROS) generated by phagocytes are well recognized as critical components in the innate immune system. Furthermore, cellular redox stress generated following infection with a number of pathogenic viruses such as HIV has also been reported. We have discovered that adeno-associa...

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Veröffentlicht in:	Molecular therapy 2006-05, Vol.13 (S1), p.S313-S313
Hauptverfasser:	Zhang, Liang N., Marden, Jennifer, Yan, Ziying, Engelhardt, John F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Cystic fibrosis Fibroblasts Gene therapy Hypotheses Infections Medical research Pancreatic cancer Vectors (Biology) Viruses
Online-Zugang:	Volltext
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