313. Cell Type Specific Media Optimization for Clinical Retroviral Transduction Protocols

In order to optimize the transduction of CD34+ cells, CD34+ derived Langerhans cells (LCs) and T lymphocytes for upcoming clinical trials, we determined which medium is best suited for each cell type. Our aim is to identify the formulation providing the best cell proliferation, survival and the high...

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Veröffentlicht in:	Molecular therapy 2006-05, Vol.13 (S1), p.S119-S120
Hauptverfasser:	Stefanski, J., Borquez-Ojeda, O., Budak-Alpdogan, T., Kendle, R., Przybylowski, M., Hollyman, D., Sadelain, M., Rivière, I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Cancer Cell growth Clinical trials Gene therapy Genetics Lymphocytes Manufacturing Process controls Vectors (Biology)
Online-Zugang:	Volltext
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