Gene Therapy of [beta]c-Deficient Pulmonary Alveolar Proteinosis ([beta]c-PAP): Studies in a Murine in vivo Model

Pulmonary alveolar proteinosis (PAP) due to deficiency of the common β-chain (βc) of the interleukin-3 (IL-3)/IL-5/granulocyte-macrophage colony-stimulating factor (GM-CSF) receptors is a rare monogeneic disease characterized by functional insufficiency of pulmonary macrophages. Hematopoietic stem c...

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Veröffentlicht in:	Molecular therapy 2008-04, Vol.16 (4), p.757
Hauptverfasser:	Kleff, Veronika, Sorg, Ursula R, Bury, Carsten, Suzuki, Takuji, Rattmann, Ina, Jerabek-willemsen, Moran, Poremba, Christopher, Flasshove, Michael, Opalka, Bertram, Trapnell, Bruce, Dirksen, Uta, Moritz, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone marrow Cancer research Congenital diseases Cytokines Disease Gene therapy Granulocytes Hematology Internal medicine Medical research Pediatrics Proteins Stem cells Surfactants Vectors (Biology)
Online-Zugang:	Volltext
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