The -308 TNF[alpha] and the -174 IL-6 promoter polymorphisms associate with effective anti-TNF[alpha] treatment in seronegative spondyloarthritis

The genetic predisposition to a long-term efficacy of anti-tumor necrosis factor (TNF)a treatment in seronegative spondyloarthritis (SpA) was investigated by analysing the possible correlation between several single nucleotide gene polymorphisms and the retention rate of anti-TNF[alpha] therapies. W...

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Veröffentlicht in:	The pharmacogenomics journal 2016-06, Vol.16 (3), p.238
Hauptverfasser:	Fabris, M, Quartuccio, L, Fabro, C, Sacco, S, Lombardi, S, Ramonda, R, Biasi, D, Punzi, D, Adami, S, Olivieri, I, Curcio, F, De Vita, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Development and progression Drug metabolism Genetic aspects Health aspects Promoters (Genetics) Properties Single nucleotide polymorphisms Spondyloarthropathies Tumor necrosis factor
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