Adverse Effects of AMP-Activated Protein Kinase [alpha]2-Subunit Deletion and High-Fat Diet on Heart Function and Ischemic Tolerance in Aged Female Mice

AMP-activated protein kinase (AMPK) plays a role in metabolic regulation under stress conditions, and inadequate AMPK signaling may be also involved in aging process. The aim was to find out whether AMPK α2-subunit deletion affects heart function and ischemic tolerance of adult and aged mice. AMPK α...

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Veröffentlicht in:	Physiological research 2016-01, Vol.65 (1), p.33
Hauptverfasser:	Slámová, K, Papousek, F, Janovská, P, Kopecký, J, Kolár, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aging Diet Fatty acids Heart Hypoxia Ischemia Kinases Laboratory animals Metabolic disorders Proteins Rodents
Online-Zugang:	Volltext
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