Histological assessment of hard and soft tissues surrounding a novel ceramic implant: a pilot study in the minipig
Objective The aim of this study was to investigate clinical and soft/hard tissues histomorphological outcomes of a ceramic implant comparatively to a titanium implant in a minipig model. Material and Methods Eighteen soft tissue level implants (9 Ceramic with ZLA® surface as test, and 9 titanium SLA...
Gespeichert in:
| Veröffentlicht in: | Journal of clinical periodontology 2016-06, Vol.43 (6), p.538-546 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 546 |
|---|---|
| container_issue | 6 |
| container_start_page | 538 |
| container_title | Journal of clinical periodontology |
| container_volume | 43 |
| creator | Liñares, Antonio Grize, Leticia Muñoz, Fernando Pippenger, Benjamin Evans Dard, Michel Domken, Olivier Blanco-Carrión, Juan |
| description | Objective
The aim of this study was to investigate clinical and soft/hard tissues histomorphological outcomes of a ceramic implant comparatively to a titanium implant in a minipig model.
Material and Methods
Eighteen soft tissue level implants (9 Ceramic with ZLA® surface as test, and 9 titanium SLActive® as control, Institut Straumann, Basel, Switzerland) were randomly placed into the mandible of 6 minipigs (n = 6). Two months later, animals were sacrificed and block biopsies were obtained to assess histomorphological outcomes. Unadjusted paired comparisons, of both groups were performed using the Wilcoxon signed rank test. The Dunnett–Hsu test was used to adjust for multiple comparisons.
Results
All implants showed excellent integration into bone and soft tissue. The fBIC (distance implant shoulder to most coronal implant contact) and BIC% (percentage bone‐to‐implant contact) were for both groups; test: 3.95 mm and 85.4%; control 3.97 mm and 84.3% respectively. No difference in peri‐implant mucosa height was found, however, the sulcular epithelium was significantly shorter for the ZrO2 (mean: 0.76, 95%CI: 0.46–1.06) than for the Ti (mean: 1.40, 95%CI: 1.10–1.70) (p = 0.0090).
Conclusions
Within the limits of this pilot study, no difference was found between the ceramic implant with ZLA® surface and a titanium implant in terms of bone tissue integration. Furthermore, the epithelial attachment favoured this ceramic implant over titanium. |
| doi_str_mv | 10.1111/jcpe.12543 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1789684823</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4059998321</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4283-4d32a14e72cea8c37f8c5caab500ce616ebb396c781bcd69c8496bf924e302593</originalsourceid><addsrcrecordid>eNp9kU9P3DAQxa0KVBbaCx8AWeqtUsCOE8furVrR5Z-Aqq3KzXKcyeJtYgfbAfbbN7DAkbnMYX7vzegNQvuUHNKpjlZmgEOalwX7gGaUE5KRkt5soRlhhGVcVnIH7ca4IoRWjLGPaCfnkksh5QyFExuT7_zSGt1hHSPE2INL2Lf4VocGa9fg6NuEk41xhIjjGIIfXWPdEmvs_D102EDQvTXY9kOnXfo2DQbb-YRjGps1tg6nW8C9dXawy09ou9VdhM8vfQ_9-XH8e36SXVwtTuffLzJT5IJlRcNyTQuocgNaGFa1wpRG67okxACnHOqaSW4qQWvTcGlEIXndyrwARvJSsj30ZeM7BH83XZ7Uyo_BTSsVrYTkohA5m6ivG8oEH2OAVg3B9jqsFSXqKV71FK96jneCD14sx7qH5g19zXMC6AZ4sB2s37FSZ_Pr41fTbKOZPgGPbxod_ilesapUfy8X6hc5p-eLnzeKs_-3pJX0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1789684823</pqid></control><display><type>article</type><title>Histological assessment of hard and soft tissues surrounding a novel ceramic implant: a pilot study in the minipig</title><source>MEDLINE</source><source>Wiley Online Library</source><creator>Liñares, Antonio ; Grize, Leticia ; Muñoz, Fernando ; Pippenger, Benjamin Evans ; Dard, Michel ; Domken, Olivier ; Blanco-Carrión, Juan</creator><creatorcontrib>Liñares, Antonio ; Grize, Leticia ; Muñoz, Fernando ; Pippenger, Benjamin Evans ; Dard, Michel ; Domken, Olivier ; Blanco-Carrión, Juan</creatorcontrib><description>Objective
The aim of this study was to investigate clinical and soft/hard tissues histomorphological outcomes of a ceramic implant comparatively to a titanium implant in a minipig model.
Material and Methods
Eighteen soft tissue level implants (9 Ceramic with ZLA® surface as test, and 9 titanium SLActive® as control, Institut Straumann, Basel, Switzerland) were randomly placed into the mandible of 6 minipigs (n = 6). Two months later, animals were sacrificed and block biopsies were obtained to assess histomorphological outcomes. Unadjusted paired comparisons, of both groups were performed using the Wilcoxon signed rank test. The Dunnett–Hsu test was used to adjust for multiple comparisons.
Results
All implants showed excellent integration into bone and soft tissue. The fBIC (distance implant shoulder to most coronal implant contact) and BIC% (percentage bone‐to‐implant contact) were for both groups; test: 3.95 mm and 85.4%; control 3.97 mm and 84.3% respectively. No difference in peri‐implant mucosa height was found, however, the sulcular epithelium was significantly shorter for the ZrO2 (mean: 0.76, 95%CI: 0.46–1.06) than for the Ti (mean: 1.40, 95%CI: 1.10–1.70) (p = 0.0090).
Conclusions
Within the limits of this pilot study, no difference was found between the ceramic implant with ZLA® surface and a titanium implant in terms of bone tissue integration. Furthermore, the epithelial attachment favoured this ceramic implant over titanium.</description><identifier>ISSN: 0303-6979</identifier><identifier>EISSN: 1600-051X</identifier><identifier>DOI: 10.1111/jcpe.12543</identifier><identifier>PMID: 26969899</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Animals ; biological width ; ceramic implant ; Ceramics ; collagen fibres ; Dental Implants ; Dentistry ; minipig model ; Osseointegration ; Pilot Projects ; Swine ; Swine, Miniature ; Titanium ; Transplants & implants ; zirconia ; ZLA</subject><ispartof>Journal of clinical periodontology, 2016-06, Vol.43 (6), p.538-546</ispartof><rights>2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><rights>2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2016 John Wiley & Sons A/S</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4283-4d32a14e72cea8c37f8c5caab500ce616ebb396c781bcd69c8496bf924e302593</citedby><cites>FETCH-LOGICAL-c4283-4d32a14e72cea8c37f8c5caab500ce616ebb396c781bcd69c8496bf924e302593</cites><orcidid>0000-0002-4130-1526</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjcpe.12543$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjcpe.12543$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26969899$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liñares, Antonio</creatorcontrib><creatorcontrib>Grize, Leticia</creatorcontrib><creatorcontrib>Muñoz, Fernando</creatorcontrib><creatorcontrib>Pippenger, Benjamin Evans</creatorcontrib><creatorcontrib>Dard, Michel</creatorcontrib><creatorcontrib>Domken, Olivier</creatorcontrib><creatorcontrib>Blanco-Carrión, Juan</creatorcontrib><title>Histological assessment of hard and soft tissues surrounding a novel ceramic implant: a pilot study in the minipig</title><title>Journal of clinical periodontology</title><addtitle>J Clin Periodontol</addtitle><description>Objective
The aim of this study was to investigate clinical and soft/hard tissues histomorphological outcomes of a ceramic implant comparatively to a titanium implant in a minipig model.
Material and Methods
Eighteen soft tissue level implants (9 Ceramic with ZLA® surface as test, and 9 titanium SLActive® as control, Institut Straumann, Basel, Switzerland) were randomly placed into the mandible of 6 minipigs (n = 6). Two months later, animals were sacrificed and block biopsies were obtained to assess histomorphological outcomes. Unadjusted paired comparisons, of both groups were performed using the Wilcoxon signed rank test. The Dunnett–Hsu test was used to adjust for multiple comparisons.
Results
All implants showed excellent integration into bone and soft tissue. The fBIC (distance implant shoulder to most coronal implant contact) and BIC% (percentage bone‐to‐implant contact) were for both groups; test: 3.95 mm and 85.4%; control 3.97 mm and 84.3% respectively. No difference in peri‐implant mucosa height was found, however, the sulcular epithelium was significantly shorter for the ZrO2 (mean: 0.76, 95%CI: 0.46–1.06) than for the Ti (mean: 1.40, 95%CI: 1.10–1.70) (p = 0.0090).
Conclusions
Within the limits of this pilot study, no difference was found between the ceramic implant with ZLA® surface and a titanium implant in terms of bone tissue integration. Furthermore, the epithelial attachment favoured this ceramic implant over titanium.</description><subject>Animals</subject><subject>biological width</subject><subject>ceramic implant</subject><subject>Ceramics</subject><subject>collagen fibres</subject><subject>Dental Implants</subject><subject>Dentistry</subject><subject>minipig model</subject><subject>Osseointegration</subject><subject>Pilot Projects</subject><subject>Swine</subject><subject>Swine, Miniature</subject><subject>Titanium</subject><subject>Transplants & implants</subject><subject>zirconia</subject><subject>ZLA</subject><issn>0303-6979</issn><issn>1600-051X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU9P3DAQxa0KVBbaCx8AWeqtUsCOE8furVrR5Z-Aqq3KzXKcyeJtYgfbAfbbN7DAkbnMYX7vzegNQvuUHNKpjlZmgEOalwX7gGaUE5KRkt5soRlhhGVcVnIH7ca4IoRWjLGPaCfnkksh5QyFExuT7_zSGt1hHSPE2INL2Lf4VocGa9fg6NuEk41xhIjjGIIfXWPdEmvs_D102EDQvTXY9kOnXfo2DQbb-YRjGps1tg6nW8C9dXawy09ou9VdhM8vfQ_9-XH8e36SXVwtTuffLzJT5IJlRcNyTQuocgNaGFa1wpRG67okxACnHOqaSW4qQWvTcGlEIXndyrwARvJSsj30ZeM7BH83XZ7Uyo_BTSsVrYTkohA5m6ivG8oEH2OAVg3B9jqsFSXqKV71FK96jneCD14sx7qH5g19zXMC6AZ4sB2s37FSZ_Pr41fTbKOZPgGPbxod_ilesapUfy8X6hc5p-eLnzeKs_-3pJX0</recordid><startdate>201606</startdate><enddate>201606</enddate><creator>Liñares, Antonio</creator><creator>Grize, Leticia</creator><creator>Muñoz, Fernando</creator><creator>Pippenger, Benjamin Evans</creator><creator>Dard, Michel</creator><creator>Domken, Olivier</creator><creator>Blanco-Carrión, Juan</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><orcidid>https://orcid.org/0000-0002-4130-1526</orcidid></search><sort><creationdate>201606</creationdate><title>Histological assessment of hard and soft tissues surrounding a novel ceramic implant: a pilot study in the minipig</title><author>Liñares, Antonio ; Grize, Leticia ; Muñoz, Fernando ; Pippenger, Benjamin Evans ; Dard, Michel ; Domken, Olivier ; Blanco-Carrión, Juan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4283-4d32a14e72cea8c37f8c5caab500ce616ebb396c781bcd69c8496bf924e302593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Animals</topic><topic>biological width</topic><topic>ceramic implant</topic><topic>Ceramics</topic><topic>collagen fibres</topic><topic>Dental Implants</topic><topic>Dentistry</topic><topic>minipig model</topic><topic>Osseointegration</topic><topic>Pilot Projects</topic><topic>Swine</topic><topic>Swine, Miniature</topic><topic>Titanium</topic><topic>Transplants & implants</topic><topic>zirconia</topic><topic>ZLA</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liñares, Antonio</creatorcontrib><creatorcontrib>Grize, Leticia</creatorcontrib><creatorcontrib>Muñoz, Fernando</creatorcontrib><creatorcontrib>Pippenger, Benjamin Evans</creatorcontrib><creatorcontrib>Dard, Michel</creatorcontrib><creatorcontrib>Domken, Olivier</creatorcontrib><creatorcontrib>Blanco-Carrión, Juan</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Journal of clinical periodontology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liñares, Antonio</au><au>Grize, Leticia</au><au>Muñoz, Fernando</au><au>Pippenger, Benjamin Evans</au><au>Dard, Michel</au><au>Domken, Olivier</au><au>Blanco-Carrión, Juan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Histological assessment of hard and soft tissues surrounding a novel ceramic implant: a pilot study in the minipig</atitle><jtitle>Journal of clinical periodontology</jtitle><addtitle>J Clin Periodontol</addtitle><date>2016-06</date><risdate>2016</risdate><volume>43</volume><issue>6</issue><spage>538</spage><epage>546</epage><pages>538-546</pages><issn>0303-6979</issn><eissn>1600-051X</eissn><abstract>Objective
The aim of this study was to investigate clinical and soft/hard tissues histomorphological outcomes of a ceramic implant comparatively to a titanium implant in a minipig model.
Material and Methods
Eighteen soft tissue level implants (9 Ceramic with ZLA® surface as test, and 9 titanium SLActive® as control, Institut Straumann, Basel, Switzerland) were randomly placed into the mandible of 6 minipigs (n = 6). Two months later, animals were sacrificed and block biopsies were obtained to assess histomorphological outcomes. Unadjusted paired comparisons, of both groups were performed using the Wilcoxon signed rank test. The Dunnett–Hsu test was used to adjust for multiple comparisons.
Results
All implants showed excellent integration into bone and soft tissue. The fBIC (distance implant shoulder to most coronal implant contact) and BIC% (percentage bone‐to‐implant contact) were for both groups; test: 3.95 mm and 85.4%; control 3.97 mm and 84.3% respectively. No difference in peri‐implant mucosa height was found, however, the sulcular epithelium was significantly shorter for the ZrO2 (mean: 0.76, 95%CI: 0.46–1.06) than for the Ti (mean: 1.40, 95%CI: 1.10–1.70) (p = 0.0090).
Conclusions
Within the limits of this pilot study, no difference was found between the ceramic implant with ZLA® surface and a titanium implant in terms of bone tissue integration. Furthermore, the epithelial attachment favoured this ceramic implant over titanium.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>26969899</pmid><doi>10.1111/jcpe.12543</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-4130-1526</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0303-6979 |
| ispartof | Journal of clinical periodontology, 2016-06, Vol.43 (6), p.538-546 |
| issn | 0303-6979 1600-051X |
| language | eng |
| recordid | cdi_proquest_journals_1789684823 |
| source | MEDLINE; Wiley Online Library |
| subjects | Animals biological width ceramic implant Ceramics collagen fibres Dental Implants Dentistry minipig model Osseointegration Pilot Projects Swine Swine, Miniature Titanium Transplants & implants zirconia ZLA |
| title | Histological assessment of hard and soft tissues surrounding a novel ceramic implant: a pilot study in the minipig |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T13%3A40%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Histological%20assessment%20of%20hard%20and%20soft%20tissues%20surrounding%20a%20novel%20ceramic%20implant:%20a%20pilot%20study%20in%20the%20minipig&rft.jtitle=Journal%20of%20clinical%20periodontology&rft.au=Li%C3%B1ares,%20Antonio&rft.date=2016-06&rft.volume=43&rft.issue=6&rft.spage=538&rft.epage=546&rft.pages=538-546&rft.issn=0303-6979&rft.eissn=1600-051X&rft_id=info:doi/10.1111/jcpe.12543&rft_dat=%3Cproquest_cross%3E4059998321%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1789684823&rft_id=info:pmid/26969899&rfr_iscdi=true |