ID: 108: DEUBIQUITINATING ENZYME 11 STABILIZES TGF[beta] RECEPTOR II AND REGULATES TGF[beta]1 SIGNALING IN PULMONARY FIBROBLAST

Background Protein stability is regulated by ubiquitination and deubiquitination. The ubiquitin-deubiquitination system contributes to the regulation of tumor growth factor β1 (TGFβ1) signaling. TGFβ1 mediates its signaling and pro-fibrotic effects through binding to its receptors, TGFβ receptor I (...

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Veröffentlicht in:Journal of investigative medicine 2016-04, Vol.64 (4), p.962
Hauptverfasser: Wei, J, Jacko, AM, Nan, L, Zhao, J, Tan, J, Kass, DJ, Zhao, Y
Format: Artikel
Sprache:eng
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