Phase I and Phase II Enzyme Polymorphisms and Childhood Cancer

Childhood cancers continue to be challenging clinical entities whose etiology, demographic characteristics, clinical progression, treatment efficacy, and outcomes remain incompletely understood. Research suggests that multiple environmental and genetic factors may play crucial roles in the pathophys...

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Veröffentlicht in:	Journal of Investigative Medicine 2006-09, Vol.54 (6), p.303-320
Hauptverfasser:	Swinney, Ryan, Hsu, Stephanie, Tomlinson, Gail
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adults Cancer Child Child, Preschool Clinical outcomes Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Enzymes Gene expression Genetic Predisposition to Disease Glucuronosyltransferase - genetics Glucuronosyltransferase - metabolism Glutathione Transferase - genetics Glutathione Transferase - metabolism Humans Hypertension Infant Leukemia Medical prognosis Metabolic Detoxication, Phase I - genetics Metabolic Detoxication, Phase II - genetics Metabolism Mortality Mutation Neoplasms - enzymology Neoplasms - genetics Parkinsons disease Pediatrics Polycyclic aromatic hydrocarbons Polymorphism, Genetic Research methodology Studies
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