Alterations of brain and cerebellar proteomes linked to A and tau pathology in a female triple-transgenic murine model of Alzheimer's disease

The triple-transgenic Alzheimer (3 × Tg-AD) mouse expresses mutant PS1M146V , APPswe , and tauP301L transgenes and progressively develops plaques and neurofibrillary tangles with a temporal- and region-specific profile that resembles the neuropathological progression of Alzheimer's disease (AD)...

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Veröffentlicht in:Cell death & disease 2010-10, Vol.1 (10), p.e90
Hauptverfasser: Ciavardelli, D, Silvestri, E, Viscovo, A Del, Bomba, M, Gregorio, D De, Moreno, M, Ilio, C Di, Goglia, F, Canzoniero, L M T, Sensi, S L
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Sprache:eng
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