Spontaneous deep venous thrombosis: An unrecognized entity with sorafenib
Hepatocellular carcinoma is the most common, malignant tumor of liver. Most cases of hepatocellular carcinoma are associated with either viral hepatitis or cirrhosis. But major risk factor for hepatocellular carcinoma in developing countries is mainly chronic hepatitis B. Sorafenib is one of the fir...
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| Veröffentlicht in: | Journal of cancer research and therapeutics 2015-10, Vol.11 (4), p.1029 |
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| container_title | Journal of cancer research and therapeutics |
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| creator | Madabhavi, Irappa Patel, Apurva Anand, Asha Choudhary, Mukesh Revannasiddaiah, Swaroop |
| description | Hepatocellular carcinoma is the most common, malignant tumor of liver. Most cases of hepatocellular carcinoma are associated with either viral hepatitis or cirrhosis. But major risk factor for hepatocellular carcinoma in developing countries is mainly chronic hepatitis B. Sorafenib is one of the first-line drug which has been extensively used in metastatic and inoperable hepatocellular carcinoma. We report a rare case of spontaneous deep venous thrombosis of bilateral lower limbs as an important unrecognized side effect of sorafenib. |
| doi_str_mv | 10.4103/0973-1482.154025 |
| format | Article |
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Most cases of hepatocellular carcinoma are associated with either viral hepatitis or cirrhosis. But major risk factor for hepatocellular carcinoma in developing countries is mainly chronic hepatitis B. Sorafenib is one of the first-line drug which has been extensively used in metastatic and inoperable hepatocellular carcinoma. 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| source | MEDLINE; Medknow Open Access Medical Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Abdomen Anticoagulants Antigens Antineoplastic agents Antineoplastic Agents - adverse effects Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - pathology Complications and side effects Development and progression Dosage and administration Drug therapy Hepatitis Hepatitis B Humans Liver cancer Liver cirrhosis Liver Neoplasms - drug therapy Liver Neoplasms - pathology Male Metastasis Middle Aged Niacinamide - adverse effects Niacinamide - analogs & derivatives Patient outcomes Patients Phenylurea Compounds - adverse effects Prognosis Risk factors Rodents Thrombophlebitis Thrombosis Veins & arteries Venous Thrombosis - chemically induced Venous Thrombosis - pathology |
| title | Spontaneous deep venous thrombosis: An unrecognized entity with sorafenib |
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