GSK-3[beta]-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte-neuron interactions

Glycogen synthase kinase-3β (GSK-3β) has emerged as a critical factor in several pathways involved in hippocampal neuronal maintenance and function. In Huntington's disease (HD), there are early hippocampal deficits both in patients and transgenic mouse models, which prompted us to investigate...

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Veröffentlicht in:	Cell death & disease 2016-04, Vol.7, p.e2206
Hauptverfasser:	L'episcopo, F, Drouin-ouellet, J, Tirolo, C, Pulvirenti, A, Giugno, R, Testa, N, Caniglia, S, Serapide, M F, Cisbani, G, Barker, R A, Cicchetti, F, Marchetti, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Huntingtons disease Immunohistochemistry Kinases Neurons Phosphorylation
Online-Zugang:	Volltext
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