Hypoxia-inducible factor-2[alpha] induces expression of type X collagen and matrix metalloproteinases 13 in osteoarthritic meniscal cells

Objectives To evaluate whether Hypoxia-inducible factor-2[alpha] (HIF-2[alpha]) regulates expression of endochondral ossification-related molecules in human OA meniscus. Methods Expressions of HIF-2[alpha], type X collagen (COL10), matrix metalloproteinase (MMP)-13, and vascular endothelial growth f...

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Veröffentlicht in:Inflammation research 2016-06, Vol.65 (6), p.439
Hauptverfasser: Ishizuka, Shinya, Sakai, Tadahiro, Hiraiwa, Hideki, Hamada, Takashi, Knudson, Warren, Omachi, Takaaki, Ono, Yohei, Nakashima, Motoshige, Matsukawa, Tetsuya, Oda, Tomoyuki, Takamatsu, Akira, Yamashita, Satoshi, Ishiguro, Naoki
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Sprache:eng
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