Biocatalytic Approach for the Total Synthesis of (-)-Malyngolide and Its C(5)-Epimer

An enzymatic approach has been successfully utilized in the total synthesis of (–)‐malyngolide and its C(5)‐epimer. The required configuration was established by an enzymatic kinetic resolution and Sharpless asymmetric dihydroxylation.

Bibliographische Detailangaben

Veröffentlicht in:	Helvetica chimica acta 2016-04, Vol.99 (4), p.267-272
Hauptverfasser:	Srivastava, Nikhil, Subba Reddy, Basi V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic activity Asymmetric dihydroxylation Enzymatic resolution Malyngolide δ-Lactone
Online-Zugang:	Volltext
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