Soluble CD83 ameliorates experimental colitis in mice

The physiological balance between pro- and anti-inflammatory processes is dysregulated in inflammatory bowel diseases (IBD) as in Crohn’s disease and ulcerative colitis. Conventional therapy uses anti-inflammatory and immunosuppressive corticosteroids to treat acute-phase symptoms. However, low remi...

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Veröffentlicht in:	Mucosal immunology 2014-07, Vol.7 (4), p.1006-1018
Hauptverfasser:	Eckhardt, J, Kreiser, S, Döbbeler, M, Nicolette, C, DeBenedette, M A, Tcherepanova, I Y, Ostalecki, C, Pommer, A J, Becker, C, Günther, C, Zinser, E, Mak, T W, Steinkasserer, A, Lechmann, M
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/256 631/250/347 692/699/249/2510/257 Allergology Animals Antibodies Antigens, CD - genetics Antigens, CD - metabolism Biomedical and Life Sciences Biomedicine CD83 Antigen Colitis - chemically induced Colitis - genetics Colitis - immunology Colitis - metabolism Colitis - pathology Dextran Sulfate - adverse effects Disease Models, Animal Gastroenterology Gastrointestinal Tract - immunology Gastrointestinal Tract - metabolism Gastrointestinal Tract - pathology Gene Expression Immunoglobulins - genetics Immunoglobulins - metabolism Immunology Indoleamine-Pyrrole 2,3,-Dioxygenase - antagonists & inhibitors Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism Leukocytes - immunology Leukocytes - metabolism Leukocytes - pathology Lymph Nodes - immunology Lymph Nodes - metabolism Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Mesentery Mice
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