B33 Non-neural Mitochondrial Impairment In Huntington’s Disease Patients And Minipigs Transgenic For The N-terminal Part Of Human Mutated Huntingtin

The most pathological effects of Huntington’s disease (HD) are focused on the central nervous system but numerous reports had described abnormalities in peripheral tissues. Mutant huntingtin (Htt) has been implicated in disruptions of multiple cellular processes, including mitochondrial functions wh...

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Veröffentlicht in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2014-09, Vol.85 (Suppl 1), p.A20-A21
Hauptverfasser: Hansíková, H, Rodinová, M, Spáčilová, J, Kratochvílová, H, Sládková, J, Marková, M, Mačáková, M, Bohuslavová, B, Ellederová, Z, Juhasová, J, Lišková, I, Klempir, J, Roth, J, Motlik, J, Zeman, J
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Sprache:eng
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