e0253 Epidemiological characteristics and reference ranges of brachialankle pulse wave velocity in China

Introduction The present study aimed to examine the epidemiological distribution and to develop the gender- and age-specific reference ranges of brachial-ankle pulse wave velocity (baPWV) in China. Materials and Methods A total of 21, 094 subjects (15–92 years) were recruited in a cross-sectional st...

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Veröffentlicht in:Heart (British Cardiac Society) 2010-10, Vol.96 (Suppl 3), p.A80-A80
Hauptverfasser: Lezhou, Wu, Liqiang, Zheng, Jue, Li, Dayi, Hu, Buaijiaer, Hasimu, Hong, Yuan, Jingang, Yang, Yingxian, Sun
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container_end_page A80
container_issue Suppl 3
container_start_page A80
container_title Heart (British Cardiac Society)
container_volume 96
creator Lezhou, Wu
Liqiang, Zheng
Jue, Li
Dayi, Hu
Buaijiaer, Hasimu
Hong, Yuan
Jingang, Yang
Yingxian, Sun
description Introduction The present study aimed to examine the epidemiological distribution and to develop the gender- and age-specific reference ranges of brachial-ankle pulse wave velocity (baPWV) in China. Materials and Methods A total of 21, 094 subjects (15–92 years) were recruited in a cross-sectional study which was conducted from June 2007 to June 2008 in China. The population was divided into 3 clinical subgroups in our study: (1) Subgroup 1: subjects with atherosclerotic cardiovascular diseases; (2) Subgroup 2: subjects with atherosclerotic risk factors; (3) Subgroup 3: “healthy subjects” without any atherosclerotic cardiovascular diseases and atherosclerotic risk factors. Results The average baPWV among subgroup 1 to 3 were 1,724.3±429.1, 1,603.5±358.8, and 1,389.9±288.4 cm/s, respectively. BaPWV as a variable was not fit of normal distribution in both genders. There was no significant difference between male and female for baPWV in subgroup 1 (p>0.05). While baPWV was higher in females than males in subgroup 2, it was lower in females than in males in subgroup 3 (all p
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Materials and Methods A total of 21, 094 subjects (15–92 years) were recruited in a cross-sectional study which was conducted from June 2007 to June 2008 in China. The population was divided into 3 clinical subgroups in our study: (1) Subgroup 1: subjects with atherosclerotic cardiovascular diseases; (2) Subgroup 2: subjects with atherosclerotic risk factors; (3) Subgroup 3: “healthy subjects” without any atherosclerotic cardiovascular diseases and atherosclerotic risk factors. Results The average baPWV among subgroup 1 to 3 were 1,724.3±429.1, 1,603.5±358.8, and 1,389.9±288.4 cm/s, respectively. BaPWV as a variable was not fit of normal distribution in both genders. There was no significant difference between male and female for baPWV in subgroup 1 (p&gt;0.05). While baPWV was higher in females than males in subgroup 2, it was lower in females than in males in subgroup 3 (all p&lt;0.05). BaPWV was dramatically increased with age in both genders (all p for trend&lt;0.05). The gender- and age-specified reference ranges for baPWV by percentiles in healthy subjects were presented in the study. The receiver operator characteristic curve demonstrated that a baPWV of 1,450 cm/s was useful to discriminate either cardiovascular diseases or atherosclerotic risk factors (sensitivity 62.1%, specificity 69.5%). Conclusions We should combine the reference ranges and the cutoff value of baPWV to screen and prevent atherosclerotic cardiovascular diseases in clinical practices.</description><identifier>ISSN: 1355-6037</identifier><identifier>EISSN: 1468-201X</identifier><identifier>DOI: 10.1136/hrt.2010.208967.253</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Cardiovascular Society</publisher><ispartof>Heart (British Cardiac Society), 2010-10, Vol.96 (Suppl 3), p.A80-A80</ispartof><rights>2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>Copyright: 2010 (c) 2010, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://heart.bmj.com/content/96/Suppl_3/A80.3.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://heart.bmj.com/content/96/Suppl_3/A80.3.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,780,784,3196,23571,27924,27925,77600,77631</link.rule.ids></links><search><creatorcontrib>Lezhou, Wu</creatorcontrib><creatorcontrib>Liqiang, Zheng</creatorcontrib><creatorcontrib>Jue, Li</creatorcontrib><creatorcontrib>Dayi, Hu</creatorcontrib><creatorcontrib>Buaijiaer, Hasimu</creatorcontrib><creatorcontrib>Hong, Yuan</creatorcontrib><creatorcontrib>Jingang, Yang</creatorcontrib><creatorcontrib>Yingxian, Sun</creatorcontrib><title>e0253 Epidemiological characteristics and reference ranges of brachialankle pulse wave velocity in China</title><title>Heart (British Cardiac Society)</title><addtitle>Heart</addtitle><description>Introduction The present study aimed to examine the epidemiological distribution and to develop the gender- and age-specific reference ranges of brachial-ankle pulse wave velocity (baPWV) in China. Materials and Methods A total of 21, 094 subjects (15–92 years) were recruited in a cross-sectional study which was conducted from June 2007 to June 2008 in China. The population was divided into 3 clinical subgroups in our study: (1) Subgroup 1: subjects with atherosclerotic cardiovascular diseases; (2) Subgroup 2: subjects with atherosclerotic risk factors; (3) Subgroup 3: “healthy subjects” without any atherosclerotic cardiovascular diseases and atherosclerotic risk factors. Results The average baPWV among subgroup 1 to 3 were 1,724.3±429.1, 1,603.5±358.8, and 1,389.9±288.4 cm/s, respectively. BaPWV as a variable was not fit of normal distribution in both genders. There was no significant difference between male and female for baPWV in subgroup 1 (p&gt;0.05). While baPWV was higher in females than males in subgroup 2, it was lower in females than in males in subgroup 3 (all p&lt;0.05). BaPWV was dramatically increased with age in both genders (all p for trend&lt;0.05). The gender- and age-specified reference ranges for baPWV by percentiles in healthy subjects were presented in the study. The receiver operator characteristic curve demonstrated that a baPWV of 1,450 cm/s was useful to discriminate either cardiovascular diseases or atherosclerotic risk factors (sensitivity 62.1%, specificity 69.5%). 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Liqiang, Zheng ; Jue, Li ; Dayi, Hu ; Buaijiaer, Hasimu ; Hong, Yuan ; Jingang, Yang ; Yingxian, Sun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b1943-5117c1323675ea91100431325698fc6faa0a2949d05e667d4c2cca080158ac73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lezhou, Wu</creatorcontrib><creatorcontrib>Liqiang, Zheng</creatorcontrib><creatorcontrib>Jue, Li</creatorcontrib><creatorcontrib>Dayi, Hu</creatorcontrib><creatorcontrib>Buaijiaer, Hasimu</creatorcontrib><creatorcontrib>Hong, Yuan</creatorcontrib><creatorcontrib>Jingang, Yang</creatorcontrib><creatorcontrib>Yingxian, Sun</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><jtitle>Heart (British Cardiac Society)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lezhou, Wu</au><au>Liqiang, Zheng</au><au>Jue, Li</au><au>Dayi, Hu</au><au>Buaijiaer, Hasimu</au><au>Hong, Yuan</au><au>Jingang, Yang</au><au>Yingxian, Sun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>e0253 Epidemiological characteristics and reference ranges of brachialankle pulse wave velocity in China</atitle><jtitle>Heart (British Cardiac Society)</jtitle><addtitle>Heart</addtitle><date>2010-10</date><risdate>2010</risdate><volume>96</volume><issue>Suppl 3</issue><spage>A80</spage><epage>A80</epage><pages>A80-A80</pages><issn>1355-6037</issn><eissn>1468-201X</eissn><abstract>Introduction The present study aimed to examine the epidemiological distribution and to develop the gender- and age-specific reference ranges of brachial-ankle pulse wave velocity (baPWV) in China. Materials and Methods A total of 21, 094 subjects (15–92 years) were recruited in a cross-sectional study which was conducted from June 2007 to June 2008 in China. The population was divided into 3 clinical subgroups in our study: (1) Subgroup 1: subjects with atherosclerotic cardiovascular diseases; (2) Subgroup 2: subjects with atherosclerotic risk factors; (3) Subgroup 3: “healthy subjects” without any atherosclerotic cardiovascular diseases and atherosclerotic risk factors. Results The average baPWV among subgroup 1 to 3 were 1,724.3±429.1, 1,603.5±358.8, and 1,389.9±288.4 cm/s, respectively. BaPWV as a variable was not fit of normal distribution in both genders. There was no significant difference between male and female for baPWV in subgroup 1 (p&gt;0.05). While baPWV was higher in females than males in subgroup 2, it was lower in females than in males in subgroup 3 (all p&lt;0.05). BaPWV was dramatically increased with age in both genders (all p for trend&lt;0.05). The gender- and age-specified reference ranges for baPWV by percentiles in healthy subjects were presented in the study. The receiver operator characteristic curve demonstrated that a baPWV of 1,450 cm/s was useful to discriminate either cardiovascular diseases or atherosclerotic risk factors (sensitivity 62.1%, specificity 69.5%). Conclusions We should combine the reference ranges and the cutoff value of baPWV to screen and prevent atherosclerotic cardiovascular diseases in clinical practices.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Cardiovascular Society</pub><doi>10.1136/hrt.2010.208967.253</doi><oa>free_for_read</oa></addata></record>
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