Tumour necrosis factor   and nuclear factor  B inhibit transcription of human TFF3 encoding a gastrointestinal healing peptide

Background and aims: Tumour necrosis factor α (TNF-α) induction of nuclear factor κB (NFκB) activation plays a major role in the pathogenesis of inflammatory bowel disease (IBD). Trefoil factor family peptides TFF1, TFF2, and TFF3 exert protective, curative, and tumour suppressive functions in the g...

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Veröffentlicht in:	Gut 2003-09, Vol.52 (9), p.1297-1303
1. Verfasser:	Loncar, M B
Format:	Artikel
Sprache:	eng
Schlagworte:	Disease Experiments Gangrene Gene expression Inflammatory bowel disease Peptides Plasmids Transcription factors Tumor necrosis factor-TNF Wound healing
Online-Zugang:	Volltext
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