Rituximab therapy for chronic periaortitis

In a recent report, one patient with periaortitis secondary to IgG4-related systemic disease was successfully treated with rituximab, although the response of the retroperitoneal mass was not described. 8 Rituximab is increasingly used in different autoimmune disorders such as rheumatoid arthritis,...

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Veröffentlicht in:Annals of the rheumatic diseases 2012-07, Vol.71 (7), p.1262-1264
Hauptverfasser: Maritati, Federica, Corradi, Domenico, Versari, Annibale, Casali, Massimiliano, Urban, Maria Letizia, Buzio, Carlo, Vaglio, Augusto
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container_end_page 1264
container_issue 7
container_start_page 1262
container_title Annals of the rheumatic diseases
container_volume 71
creator Maritati, Federica
Corradi, Domenico
Versari, Annibale
Casali, Massimiliano
Urban, Maria Letizia
Buzio, Carlo
Vaglio, Augusto
description In a recent report, one patient with periaortitis secondary to IgG4-related systemic disease was successfully treated with rituximab, although the response of the retroperitoneal mass was not described. 8 Rituximab is increasingly used in different autoimmune disorders such as rheumatoid arthritis, systemic lupus erythematosus and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides. 9 CP is also thought to have an autoimmune background, given its association with autoimmune diseases 6 10 and with the autoimmunity-predisposing HLA-DRB1*03 allele. 11 The efficacy of rituximab also suggests a crucial pathogenetic role for B cells in CP. [...]rituximab may be effective in CP.
doi_str_mv 10.1136/annrheumdis-2011-201166
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subjects Abdomen
Aged, 80 and over
Antibodies, Monoclonal, Murine-Derived - therapeutic use
Autoimmune diseases
Back pain
Biological and medical sciences
Disease
Diseases of the osteoarticular system
Drug Substitution
Female
Humans
Immunologic Factors - therapeutic use
Immunomodulators
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Remission Induction
Retroperitoneal Fibrosis - diagnosis
Retroperitoneal Fibrosis - drug therapy
Rituximab
Treatment Outcome
title Rituximab therapy for chronic periaortitis
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