AB0036 Analysis of genetic polymorphisms in folate pathway affecting the efficacy of methotrexate in japanese patients with rheumatoid arthritis

Background Low-dose methotrexate (MTX) is an anchor drug in the medication of rheumatoid arthritis (RA). However, MTX exhibited large inter-individual and inter-ethnic differences in the dose required for its anti-inflammatory effect. In order to maintain the low disease activity, there are also the...

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Veröffentlicht in:Annals of the rheumatic diseases 2013-06, Vol.71 (Suppl 3), p.639-639
Hauptverfasser: Tazoe, Y., Hayashi, H., Tsuboi, S., Morishita, M., Arai, T., Ohshima, M., Matsuyama, T., Kosuge, K., Yamada, H., Tsuji, D., Inoue, K., Itoh, K.
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Sprache:eng
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