$SP0189 Induction of Remission by Low-Dose IL-2-Therapy in One SLE Patient with Increased Disease Activity Refractory to Standard Therapies$

SP0189 Induction of Remission by Low-Dose IL-2-Therapy in One SLE Patient with Increased Disease Activity Refractory to Standard Therapies

IL-2 deficiency and associated regulatory T cell (Treg) defects critically contribute to SLE pathogenesis. In our previous translational work we proved the efficacy and safety of a low-dose IL-2 therapy in animal models and identified a reversible IL-2 deprivation of Treg also in human SLE patients....

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Veröffentlicht in:	Annals of the rheumatic diseases 2014-06, Vol.73 (Suppl 2), p.50
1. Verfasser:	Humrich, J.Y.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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