SAT0260 Biomarkers Associated with Rheumatoid Arthritis Disease Activity Including Joint Damage Correlate with Changes in Clinical Response in Subjects Treated with Mavrilimumab at Doses above 10 Mg

Background Mavrilimumab is a human monoclonal antibody targeting the alpha subunit of GM-CSF receptor and was recently evaluated in RA subjects in a phase 2a study (EARTH). Results reported from the European (EU) cohort demonstrated that mavrilimumab shows activity in subjects with moderate to sever...

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Veröffentlicht in:Annals of the rheumatic diseases 2014-06, Vol.73 (Suppl 2), p.687
Hauptverfasser: White, W., Ryan, P.C., Guo, X., Sinibaldi, D., Ranganna, G., Godwood, A., Saurigny, D., Close, D., Eck, S., Wilkins, D., Roskos, L., Sleeman, M., Li, W., Cavet, G., Defranoux, N.
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Sprache:eng
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