FRI0052 The cox/prostaglandin-E2 pathway is critical for autocrine IL-17A production by TH17 cells upon synovial fibroblast interaction

Background Recently, the authors have shown that Th17, but not Th1 cells, from patients with early rheumatoid arthritis (RA) are potent activators of synovial fibroblasts (RASF) resulting inautocrine IL-17A production. This IL-17A production results in a pro-inflammatory loop, which is characterized...

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Veröffentlicht in:	Annals of the rheumatic diseases 2013-06, Vol.71 (Suppl 3), p.326-327
Hauptverfasser:	Paulissen, S.M.J., van Hamburg, J.P., Davelaar, N., Asmawidjaja, P.S., Hazes, J.M.W., Lubberts, E.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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