A9.3 Hydrogen sulfide and MEK1 inhibition reduce IL-1[beta]-induced activation of fibroblast-like synoviocytes

Background and Objectives In the pathophysiology of osteoarthritis (OA) the secretion of the pro-inflammatory cytokine interleukin (IL)-1β is among the critical steps mediating the aberrant degenerative processes in which activated fibroblast-like synoviocytes (FLS) play a pivotal role. The major go...

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Veröffentlicht in:	Annals of the rheumatic diseases 2014-03, Vol.73, p.A93
Hauptverfasser:	Sieghart, D, Kiener, H P, Kloesch, B, Steiner, G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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