OP0075 A 6-Month, Phase 2, Open–Label, Single-Arm Study to Evaluate the Safety and Efficacy of Treatment with Canakinumab of Pediatric Patients with Colchicine Resistant Familial Mediterranean Fever

Background Familial Mediterranean fever (FMF) is the most common hereditary autoinflammatory syndrome, affecting > 100,000 people. FMF is caused by mutations in the MEFV gene, which encodes for the pyrin protein that is part of the inflammation complex that activates IL-1β. Evidence from case rep...

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Veröffentlicht in:	Annals of the rheumatic diseases 2013-06, Vol.72 (Suppl 3), p.A75-A76
Hauptverfasser:	Brik, R., Butbul Aviel, Y., Lubin, S., Ben Dayan, E., Tseng, L., Hashkes, P. J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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