OP0193 Synovial Fluid Neutrophils Undergoing Netosis Contribute to Joint Inflammation by Producing Citrullinated Autoantigens

Background Anti-citrullinated protein antibodies (ACPA) are characteristically detected in patients with rheumatoid arthritis (RA) and growing evidence suggests that they are involved in disease pathogenesis. During disease flares large numbers of neutrophils enter the joint space of RA patients. Th...

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Veröffentlicht in:Annals of the rheumatic diseases 2013-06, Vol.72 (Suppl 3), p.A118
Hauptverfasser: Spengler, J., Lugonja, B., Creese, A., Nicholas, A., Milward, M., Pearson, M., Buckley, C., Filer, A., Raza, K., Cooper, P. R., Chapple, I. L., Scheel-Toellner, D.
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Sprache:eng
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