The relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis

Objectives To analyse the relationship between the type I interferon (IFN) signature and the response to rituximab in rheumatoid arthritis (RA) patients. In peripheral blood mononuclear cells from baseline the presence of an IFN signature was analysed by measuring the expression levels of three IFN...

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Veröffentlicht in:Annals of the rheumatic diseases 2010-03, Vol.69 (Suppl 2), p.A14-A15
Hauptverfasser: Thurlings, R M, Boumans, M, Tekstra, J, Vos, K, van Westing, D M, van Baarsen, L G, Bos, C, Kirou, K A, Gerlag, D M, Crow, M K, Verweij, C L, Tak, P P
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container_end_page A15
container_issue Suppl 2
container_start_page A14
container_title Annals of the rheumatic diseases
container_volume 69
creator Thurlings, R M
Boumans, M
Tekstra, J
Vos, K
van Westing, D M
van Baarsen, L G
Bos, C
Kirou, K A
Gerlag, D M
Crow, M K
Verweij, C L
Tak, P P
description Objectives To analyse the relationship between the type I interferon (IFN) signature and the response to rituximab in rheumatoid arthritis (RA) patients. In peripheral blood mononuclear cells from baseline the presence of an IFN signature was analysed by measuring the expression levels of three IFN response genes by quantitative PCR.
doi_str_mv 10.1136/ard.2010.129585k
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Funding
Rheumatoid arthritis
title The relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis
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