The relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis

The relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis

Objectives To analyse the relationship between the type I interferon (IFN) signature and the response to rituximab in rheumatoid arthritis (RA) patients. In peripheral blood mononuclear cells from baseline the presence of an IFN signature was analysed by measuring the expression levels of three IFN...

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Veröffentlicht in:Annals of the rheumatic diseases 2010-03, Vol.69 (Suppl 2), p.A14-A15
Hauptverfasser: Thurlings, R M, Boumans, M, Tekstra, J, Vos, K, van Westing, D M, van Baarsen, L G, Bos, C, Kirou, K A, Gerlag, D M, Crow, M K, Verweij, C L, Tak, P P
Format: Artikel
Sprache:eng
Schlagworte:
Biological activity
Funding
Rheumatoid arthritis
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Zusammenfassung:Objectives To analyse the relationship between the type I interferon (IFN) signature and the response to rituximab in rheumatoid arthritis (RA) patients. In peripheral blood mononuclear cells from baseline the presence of an IFN signature was analysed by measuring the expression levels of three IFN response genes by quantitative PCR.
ISSN:0003-4967
1468-2060
DOI:10.1136/ard.2010.129585k