Identification and quantitation of lipid C=C location isomers: A shotgun lipidomics approach enabled by photochemical reaction

The field of lipidomics has been significantly advanced by mass spectrometric analysis. The distinction and quantitation of the unsaturated lipid isomers, however, remain a long-standing challenge. In this study, we have developed an analytical tool for both identification and quantitation of lipid...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2016-03, Vol.113 (10), p.2573-2578
Hauptverfasser:	Ma, Xiaoxiao, Chong, Leelyn, Tian, Ran, Shi, Riyi, Hu, Tony Y., Ouyang, Zheng, Xia, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Brain Chemistry Chemical reactions Fatty acids Fatty Acids, Unsaturated - analysis Fatty Acids, Unsaturated - chemistry Glycerophospholipids - analysis Glycerophospholipids - chemistry Isomerism Lipids Lipids - analysis Lipids - chemistry Mammary Glands, Animal - chemistry Mammary Neoplasms, Animal - chemistry Mass spectrometry Mice Models, Chemical Molecular Structure Photochemical Processes Photochemistry Physical Sciences Rats Rodents Tandem Mass Spectrometry - methods
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