pH-dependent inhibition of K^sub 2P^3.1 prolongs atrial refractoriness in whole hearts

In isolated human atrial cardiomyocytes, inhibition of K^sub 2P^3.1 K^sup +^ channels results in action potential (action potential duration (APD)) prolongation. It has therefore been postulated that K^sub 2P^3.1 (KCNK3), together with K^sub 2P^9.1 (KCNK9), could represent novel drug targets for the...

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Veröffentlicht in:	Pflügers Archiv 2016-04, Vol.468 (4), p.643
Hauptverfasser:	Skarsfeldt, Mark A, Jepps, Thomas A, Bomholtz, Sofia H, Abildgaard, Lea, Sørensen, Ulrik S, Gregers, Emilie, Svendsen, Jesper H, Diness, Jonas G, Grunnet, Morten, Schmitt, Nicole, Olesen, Søren-peter, Bentzen, Bo H
Format:	Artikel
Sprache:	eng
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