Construction of Chiral Multi-Functionalized Polyheterocyclic Benzopyran Derivatives by Using an Asymmetric Organocatalytic Domino Reaction

The asymmetric domino reaction of various α,α‐dicyano olefins to 3‐nitro‐2H‐chromenes was studied employing readily available cinchona‐derived bifunctional thioureas as organocatalysts. These new transformations were highly regio‐, chemo‐, diastereo‐, and enantioselective simultaneously giving chira...

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Veröffentlicht in:European journal of organic chemistry 2012-12, Vol.2012 (35), p.6924-6932
Hauptverfasser: Guo, Zhi-Wei, Li, Xin-Sheng, Zhu, Wei-Dong, Xie, Jian-Wu
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Sprache:eng
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