Targeting SIRP-[alpha] protects from type 2-driven allergic airway inflammation

The interplay between innate and adaptive immune responses is essential for the establishment of allergic diseases. CD47 and its receptor, signal regulatory protein [alpha] (SIRP-[alpha]), govern innate cell trafficking. We previously reported that administration of CD47+/+ but not CD47-/- SIRP-[alp...

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Veröffentlicht in:European journal of immunology 2010-12, Vol.40 (12), p.3510
Hauptverfasser: Raymond, Marianne, Quang Van, Vu, Rubio, Manuel, Welzenbach, Karl, Sarfati, Marika
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Sprache:eng
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