Dimedone-catalyzed Addition of Amines into Cyano Group： Facile Synthesis of Thiazol-2-yl Substituted E-Acrylonitriles

An efficient dimedone-catalyzed synthesis of highly functionalized thiazol-2-yl substituted E-acrylonitrile derivatives has been established through two-step reaction of a-thiocyanate ketones with malononitrile and amines. The a-thiocyanate ketones were subjected with malononitrile to provide thiazo...

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Veröffentlicht in:	Chinese journal of chemistry 2012-07, Vol.30 (7), p.1617-1623
1. Verfasser:	朱伟军 屠兴超 冯惠 屠蔓苏 姜波 吴飞跃 屠树江
Format:	Artikel
Sprache:	eng
Schlagworte:	addition reaction dimedone-catalyzed synthesis E-acrylonitriles heterocycles microwave heating 丙烯腈 两步反应 催化合成 噻唑 氰基 胺 衍生物 酮
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