LiBr as an Efficient Catalyst for One-pot Synthesis of Hantzsch 1,4-Dihydropyridines under Mild Conditions
A simple, inexpensive and efficient one-pot synthesis of 1,4-dihydropyridines has been accomplished via lithium bromide-catalyzed Hantzsch three-component condensation reaction of an aldehyde, α,β-ketoester and ammonium acetate in acetonitrile at room temperature in good to excellent yields. The pre...
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| Veröffentlicht in: | Chinese journal of chemistry 2011, Vol.29 (1), p.118-122 |
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| container_title | Chinese journal of chemistry |
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| creator | Yadav, D. K. Patel, R. Srivastava, V. P. Watal, G. Yadav, L. D. S |
| description | A simple, inexpensive and efficient one-pot synthesis of 1,4-dihydropyridines has been accomplished via lithium bromide-catalyzed Hantzsch three-component condensation reaction of an aldehyde, α,β-ketoester and ammonium acetate in acetonitrile at room temperature in good to excellent yields. The present protocol is applicable to wide range of substrates including aliphatic, aromatic and heterocyclic aldehydes affording 1,4-dihydropyridines. |
| doi_str_mv | 10.1002/cjoc.201190036 |
| format | Article |
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The present protocol is applicable to wide range of substrates including aliphatic, aromatic and heterocyclic aldehydes affording 1,4-dihydropyridines.</description><subject>1,4‐dihydropyridines</subject><subject>4-dihydropyridines</subject><subject>cyclization</subject><subject>Hantzsch reaction</subject><subject>lithium bromide</subject><subject>multicomponent reactions</subject><subject>one-pot procedure</subject><subject>一锅合成</subject><subject>三组分</subject><subject>二氢吡啶</subject><subject>杂环醛</subject><subject>温和条件</subject><subject>溴化锂</subject><subject>缩合反应</subject><subject>高效催化剂</subject><issn>1001-604X</issn><issn>1614-7065</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNqFkE1PGzEQhleoSFDolbPVXrvp-Ns5tstXUSASUJWb5fV6iUNqB9sRbH89i4JQbz3NaPQ8M6O3qo4wTDAA-WaX0U4IYDwFoGKn2scCs1qC4B_GHgDXAtjdXvUx5-XIS0nEfrWc-R8JmYxMQCd97613oaDGFLMackF9TGgeXL2OBd0MoSxc9hnFHp2bUP5mu0D4K6uP_WLoUlwPyXc-uIw2oXMJXfpVh5oYOl98DPmw2u3NKrtPb_Wg-nV6ctuc17P52c_m-6y2VBFRc0asxQ5kx5Tghqspoa3BlLcgWtcCYWYcSNOpljuCsRJTbrkwhnDBjKL0oPqy3btO8XHjctHLuElhPKmxFEKBoEyO1GRL2RRzTq7X6-T_mDRoDPo1T_2ap37PcxSmW-HJr9zwH1o3F_PmX7feuj4X9_zumvSghaSS699XZ_qYX94qdn2h2ch_fntuEcP9ow_3ujX2oR8vayopcOCKvgB5iZMP</recordid><startdate>2011</startdate><enddate>2011</enddate><creator>Yadav, D. 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| identifier | ISSN: 1001-604X |
| ispartof | Chinese journal of chemistry, 2011, Vol.29 (1), p.118-122 |
| issn | 1001-604X 1614-7065 |
| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | 1,4‐dihydropyridines 4-dihydropyridines cyclization Hantzsch reaction lithium bromide multicomponent reactions one-pot procedure 一锅合成 三组分 二氢吡啶 杂环醛 温和条件 溴化锂 缩合反应 高效催化剂 |
| title | LiBr as an Efficient Catalyst for One-pot Synthesis of Hantzsch 1,4-Dihydropyridines under Mild Conditions |
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