Leptin regulates sugar and amino acids transport in the human intestinal cell line Caco-2

Aim Studies in rodents have shown that leptin controls sugars and glutamine entry in the enterocytes by regulating membrane transporters. Here, we have examined the effect of leptin on sugar and amino acids absorption in the human model of intestinal cells Caco‐2 and investigated the transporters in...

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Veröffentlicht in:	Acta Physiologica 2012-05, Vol.205 (1), p.82-91
Hauptverfasser:	Fanjul, C., Barrenetxe, J., Iñigo, C., Sakar, Y., Ducroc, R., Barber, A., Lostao, M. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Transport Systems - metabolism amino acid transporters Biological and medical sciences Biological Transport - drug effects Caco-2 Cells Cells, Cultured Fundamental and applied biological sciences. Psychology Glutamine - metabolism Glutamine - pharmacology Humans leptin Leptin - metabolism Leptin - pharmacology sodium-dependent glucose transporter 1 Sodium-Glucose Transport Proteins - metabolism Vertebrates: anatomy and physiology, studies on body, several organs or systems Western blot
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